![]() The more advanced brain templates using multiple subjects have higher signal-to-noise ratio, provide better contrast between grey matter and white matter, and quantify typical variations within the study cohort or the population of interest. Digital brain templates, or atlases, generated either from a single-subject or from multiple subjects, have begun to replace the conventional printed brain template (e.g., Talairach and Tournoux atlas). ![]() We conclude by discussing the scope of brain templates as a research tool and their application in various neuroimaging modalities.Ī brain template is a specific anatomical presentation of the brain depicting finer anatomical details (e.g., nuclei, cortical areas). The manuscript also provides the automated workflow-based protocol for designing a population-specific brain atlas from structural MRI data using LONI Pipeline graphical workflow environment. A chronological outline of the development of brain template design, starting from the Talairach and Tournoux atlas to the Chinese brain template (to date), along with their respective detailed construction protocols provides the backdrop to this manuscript. This manuscript provides a comprehensive review of the history, construction and application of brain atlases. HUMAN BRAIN MAPPING TEMPLATE REGISTRATIONFurther, there are certain differences (e.g., brain shape and size) in the brains of populations of different origin and during diseased conditions like in Alzheimer’s disease (AD), population and disease-specific brain templates may be considered crucial for accurate registration and subsequent analysis of fMRI as well as other neuroimaging data. Brain templates also find application in other neuroimaging modalities, such as diffusion tensor imaging and multi-voxel spectroscopy. Analysis of fMRI data requires the registration of the data to a reference brain template in order to identify the activated brain regions. On the other hand, functional MRI (fMRI) provides information on the brain activity during performance of a specific task. It does not store any personal data.Structural magnetic resonance imaging (MRI) provides anatomical information about the brain in healthy as well as in diseased conditions. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. The cookie is used to store the user consent for the cookies in the category "Performance". This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. ![]() The cookies is used to store the user consent for the cookies in the category "Necessary". The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The cookie is used to store the user consent for the cookies in the category "Analytics". These cookies ensure basic functionalities and security features of the website, anonymously. Necessary cookies are absolutely essential for the website to function properly.
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